I use these on primarily on two different routes. 1) Commuted about twice each week going through often damp forest paved roads through central Florida about 112 miles each way going roughly 60 mph, and; 2) Commuted about 50 miles on interstates averaging about 75 mph. I drive a 2014 Ford Taurus with the Michelin Primacy MXM4 245/45R20 99V tires. To date, I have 5/32 tread depth remaining with 60,000 miles on the original set of these OEM tires. I rotate the tires with each oil change. When worn, the same tire type will exchange them. They've handled flawlessly, no issues. Great stopping and handling without road noise.
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Tires are usually taken for granted, until the road puts them to the test.